6 Months Internship - New Biotics Identification By In Silico Biology W - M H/F - 59

As a global key player in yeasts and fermentation, Lesaffre designs, manufactures and markets innovative solutions forBaking, Food taste & pleasure, Health care and Biotechnology.

Family group born in northern France in 1853, now a multi-national and a multicultural company, Lesaffre is committed toworking with confidence to better nourish and protect the planet.
In close collaboration with its clients and partners, Lesaffre employs11 000 peoplein more than50 countries.

Lesaffre achieves a turnover of 3 billion Euros.This internship will BE carried out between three research entities (Biodata, Microorganisms and Nutrition, Microbiota and Health) of the Lesaffre Institute of Science and Technology. Your role will consist in digging into our microorganism collection to identify specific transporters and enzymatic activities related to putative functions. Within the time frame of the internships two to three research targets will BE explored (dry-lab step 1). This initial stage should reduce the number of candidates for follow-up validation work in the laboratory (wet-lab step 2) with ad hoc assays (microbiology or cell biology) to assess potential biotic candidates (yeast or bacteria).

Key Responsibilities
- Collaborate with subject matter experts in bioinformatics and host and microbe interactions to understand the research context and gather the relevant publications.
- Acquire competence and autonomy in genomic data mining.
- Identify and extract key genomic features from whole genome sequences and comparison with established benchmark.
- Propose an experimental validation strategy with microbiologists or cell biologists.
- Perform first proof of concept validation assay